Toxoplasmosis and Anxiety: A Review Study

Author:

Dowran Behnaz1,Khanaliha Khadijeh2ORCID,Mohammadzadeh Tahereh3

Affiliation:

1. Behavioral Sciences Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

2. Research Center of Pediatric Infectious Diseases, Institute of Immunology and Infectious Diseases, Iran University of Medical Sciences, Tehran, Iran

3. Health Research Center, Life Style Institute, Baqiyatallah University of Medical Sciences, Tehran, Iran

Abstract

Background: Toxoplasmosis, a significant zoonotic parasitic disease with serious health problems, is caused by apicomplexan protozoa, Toxoplasma gondii. Evidence has shown that Toxoplasma can also lead to psychological diseases. Objectives: The aim of this study was to collect information on the relationship between anxiety and toxoplasmosis. Materials and Methods: PubMed, Google Scholar, Noormags, and Magiran databases were searched for studies published from 2010 to October 2020. Studies that assessed the relationship between toxoplasmosis/toxoplasma and anxiety were included in the analysis. Synthesis of the results was the primary strategy for data analysis. Results: According to the inclusion and exclusion criteria, 16 articles were selected. They had been conducted in Iran, the USA, Turkey, the Czech Republic, Finland, Mexico, Austria, and Denmark. In general, the results of 8 out of 11 investigated human studies indicated that T. gondii infection was associated with anxiety. Moreover, five of them were non-human studies, and most of them showed that T. gondii caused anxiety-related symptoms. Conclusion: The results of most studies showed that toxoplasmosis could be associated with anxiety. However, more studies are needed to look closely at how anxiety relates to this parasite.

Publisher

Maad Rayan Publishing Company

Subject

General Agricultural and Biological Sciences

Reference30 articles.

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5. Gharavi MJ, Roozbehani M, Miahipour A, et al. Prevalence of anti-Toxoplasma gondii antibodies in young Iranians: the CASPIAN III study. Arch Pediatr Infect Dis. 2018;6(1).

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