Description and management of non-metastatic thoracic myxofibrosarcoma: a case report

Author:

Aalami Amir Hossein1ORCID,Amirabadi Amir23ORCID,Hosseini Mojahed Fatemeh4ORCID,Ayatllahi Ali5ORCID

Affiliation:

1. Department of Biology, Mashhad Branch, Islamic Azad University, Mashhad, Iran.

2. Solid Tumors Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.

3. Reza Radiation Oncology Center, Mashhad, Iran.

4. Department of Medical Sciences, Mashhad Medical Sciences Branch, Islamic Azad University, Mashhad, Iran.

5. Department of Pathology, Mashhad University of Medical Sciences, Mashhad, Iran.

Abstract

Myxofibrosarcoma is a soft tissue sarcoma (STS) prevailing in the elderly and is associated with metastasis and mortality. In this case, an 88-year-old male is presented with a progressively enlarging mass in the posterior thorax. The physical examination revealed a solid, irregular, painful mass on palpation. Doppler ultrasonography and high-resolution computed tomography (CT) scan revealed a 60 × 38 mm hypoechoic tumor in the left paraspinal thoracic area with a little vascularity with no adherence and invasion. Radical excisional surgery was performed. The histopathology findings were in line with myxofibrosarcoma except for CD34. He underwent high dose radiotherapy due to the reported not assessable margins at one side. The patient was asymptomatic and recurrent free in the 12 months follow up assessment. It was the first known case of the non-metastatic intermediate grade of myxofibrosarcoma in the thorax. Due to its deceptive findings, myxofibrosarcoma should always be considered in the assessment of chest wall tumors.

Publisher

Maad Rayan Publishing Company

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