Severe thrombocytopenic purpura due to rubella infection in a patient with systemic lupus erythematosus-Reference-Cited by-同舟云学术

Severe thrombocytopenic purpura due to rubella infection in a patient with systemic lupus erythematosus

Published:2003-02 Issue:2 Volume:12 Page:144-146
ISSN:0961-2033
Container-title:Lupus
language:en
Short-container-title:Lupus

Author:

Boehlen F¹,Balavoine J-F¹,de Moerloose P²

Affiliation:

1. Haemostasis Unit, Division of Angiology and Haemostasis, Department of Medicine, University Hospital, Geneva, Switzerland

2. Haemostasis Unit, Division of Angiology and Haemostasis, Department of Medicine, University Hospital, Geneva, Switzerland,

Abstract

We report the case of a woman suffering from systemic lupus erythematosus who developed a severe thrombocytopenic purpura (platelet count< 1 ×10 9=1) secondary to rubella infection. The search for antiplatelet antibodies revealed transient circulating anti-GPIIb-IIIa and anti-GPIb-IX platelet antibodies. After a few weeks, bound anti-GPIIb-IIIa antiplatelet antibodies were still detectable and they persisted several months after recovery, probably in relation to a mild autoimmune thrombocytopenia related to systemic lupus erythematosus. To our knowledge, this is the first case report of severe thrombocytopenic purpura due to rubella in an adult with systemic lupus erythematosus.

Publisher

SAGE Publications

Subject

Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1191/0961203303lu279cr

Reference12 articles.

1. Neonatal thrombocytopenia: incidence and characterization of maternal antiplatelet antibodies by MAIPA assay

2. Purpura in Congenital and Acquired Rubella

3. Short report: Idiopathic thrombocytopenic purpura and MMR vaccine

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