The two hit hypothesis in the antiphospholipid syndrome: acute ischaemic heart involvement after valvular replacement despite anticoagulation in a patient with secondary APS-Reference-Cited by-同舟云学术

The two hit hypothesis in the antiphospholipid syndrome: acute ischaemic heart involvement after valvular replacement despite anticoagulation in a patient with secondary APS

Published:2003-11 Issue:11 Volume:12 Page:851-853
ISSN:0961-2033
Container-title:Lupus
language:en
Short-container-title:Lupus

Author:

Bordin G¹,Boldorini R²,Meroni P L³

Affiliation:

1. Department of Internal Medicine, Azienda Ospedaliera S. Gerardo, Presidio Ospedaliero ‘Bassini’, Cinisello Balsamo, Milan, Italy,

2. Pathology Service, Ospedale Maggiore della Carità, Novara, Italy

3. Allergy and Clinical Immunology Unit, Department of Internal Medicine, University of Milan, Milan, Italy

Abstract

A patient with the antiphospholipid syndrome (APS), in whom a nonfatal myocardial infarction ensued after valvular heart replacement despite anticoagulation, is described. The report further stresses the role of concomitant risk co-factors in inducing thrombotic events and points out that cardiosurgery might represent a potential major risk for myocardial ischaemic damage in APS.

Publisher

SAGE Publications

Subject

Rheumatology

Link

http://journals.sagepub.com/doi/pdf/10.1191/0961203303lu445cr

Reference8 articles.

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4. Prevalence of Anti-cardiolipin, Anti-2Glycoprotein I, and Anti-prothrombin Antibodies in Young Patients with Epilepsy

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