Indications for manual lung hyperinflation (MHI) in the mechanically ventilated patient with chronic obstructivepulmonary disease

Abstract

Manual lung hyperinflation (MHI) can enhance secretion clearance, improve total lung/thorax compliance and assistin the resolution of acute atelectasis. To enhance secretion clearance in the intubated patient, the evidence highlights the need to maximize expiratory flow. Chronic pulmonary diseases such as chronic obstructive pulmonary disease(COPD) have often been cited as potential precautions and/or contra-indications to the use of manual lung hyperinflation (MHI). There is an absence of evidence on the effects of MHI in the patient with COPD. Research on the effects of mechanical ventilation in the patient with COPD providesa useful clinical examination of the effect of positive pressure on cardiac and pulmonary function. The potential effects of MHI in the COPD patient group were extrapolated on the basis of the MHI and mechanical ventilation literature. There is the potential for MHI to have both detrimental and beneficial effects on cardiac and pulmonary functionin patients with COPD. The potential detrimental effects of MHI may include either, increased intrinsic peep throughinadequate time for expiration by the breath delivery rate, tidal volume delivered or through the removal of appliedextemal PEEP thereby causing more dynamic airway compression compromising downward expiratory flow, which may also retard bronchial mucus transport. MHI may also increase right ventricular after load through raised intrathoracic pressures with lung hyperinflation, and may therefore impair right ventricular function in patients with evidence of cor pulmonale. There is the potential for beneficial effectsfrom MHI in the intubated COPD patient group (i.e., secretion clearance), but further research is required, especially on the effect of MHI on inspiratory and expiratory flowrate profiles in this patient group. The more controlled delivery of lung hyperinflation through the use of the mechanical ventilator may be a more optimal means of providinglunghyperinflation and shouldbe furtherinvestigated.