Hereditary Melkersson-Rosenthal syndrome and multiple sclerosis

Author:

Cabrera-Gómez J A1,Echazabal-Santana N2,Real-González Y2,García K Romero2,Sobrinho Manuel Junior2,Ocaña M A Gil2,González-Valdes N3,de Oca M L Valdes-Montes3,Cristofol-Corominas M2,de la Nuez J González3,Lahera J García3,Şuárez C Ugarte3

Affiliation:

1. International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba, ,

2. International Center of Neurologic Restoration (CIREN), Avenida 25 #15805 entre 158 y 160, Reparto Cubanacán, Playa, Ciudad de La Habana, Cuba

3. Cuban Society of Multiple Sclerosis, Havana, Cuba

Abstract

The revision of MEDLINE from 1966 to 2003 did not report any association between multiple sclerosis (MS) and Melkersson—Rosenthal syndrome (MRS). This is a case report of a 51-year-old woman, with history of four recurrent Bell’s palsies. In 1999 she developed a right facial paralysis due to a supranuclear pyramidal lesion with right monoparesis. The family history showed five relatives with recurrent Bell’s paralysis and plicata tongue. Physical examination: right Bell’s paralysis, left supranuclear facial paralysis, furrowed tongue, right hemiparesis with pallor of the optic disks. Brain magnetic resonance imaging (MRI) demonstrated the typical lesions of MS and CSF oligoclonal bands. This is the first observation of a patient with hereditary MRS and MS. The link between both diseases is discussed.

Publisher

SAGE Publications

Subject

Neurology (clinical),Neurology

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