Affiliation:
1. Nurse Maude Hospice, Christchurch
Abstract
Haloperidol is one of 20 ‘essential’ medications in palliative care. Its use is widespread in palliative care patients. The pharmacology of haloperidol is complex and the extent and severity of some of its adverse effects, particularly extrapyramidal adverse effects (EPS), may be related to the route of administration. Indications for the use of haloperidol in palliative care are nausea and vomiting and delirium. Adverse effects include EPS and QT prolongation. Sedation is not a common adverse effect of haloperidol. It is important that palliative care practitioners have a comprehensive understanding of the indications, doses, adverse effects and pharmacology of haloperidol. This review is intended to address these issues.
Subject
Anesthesiology and Pain Medicine,General Medicine
Reference34 articles.
1. The impact of the polymorphism on haloperidol pharmacokinetics and on the outcome of haloperidol treatment
2. Levy RH, Thummel KE, Trager WF, Hansten PD, Eichelbaum M eds. Metabolic drug interactions. Philadelphia, PA: Lippincott Williams and Wilkins, 2000: 247-249.
Cited by
69 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献