Ocular Syphilis: A Case of Progressive Bilateral Panuveitis

Abstract

Significance This report outlines a case of progressive bilateral granulomatous panuveitis secondary to syphilis. Purpose To describe the management of a case of progressive uveitis secondary to syphilis. Case Report A 60-year-old male with a three-month history of redness and floaters presented with bilateral chronic granulomatous anterior uveitis. He was started on difluprednate emulsion four times a day in each eye. The patient’s clinical course improved until he tapered off the drops, upon which he presented with a progressive bilateral panuveitis. A diagnostic work-up in collaboration with the hospital infectious disease department led to a diagnosis of neurosyphilis. The patient was treated with intravenous penicillin with eventual resolution of his ocular inflammation. Conclusions This case report underscores the importance of obtaining a detailed case history and taking a multi-disciplinary approach to patients with progressive uveitis. CE Notification This article is available as a COPE accredited CE course. You may take this course for 1-hour credit. Read the article and take the qualifying test to earn your credit. Click here to Enroll (https://www.crojournal.com/ocular-syphilis-a-case-of-progressive-bilateral-panuveitis) Please check COPE course expiry date prior to enrollment. The COPE course test must be taken before the course expiry date.