Correlation of salivary biomarkers with anthropometric indices for cardio-metabolic risk screening in professional undergraduates

Abstract

Introduction and Aim: The onset of cardio metabolic disorders in the later parts of adult life requires development of early screening techniques. The current study is an approach to design and evaluate the easy-to-use method for the diagnosis of cardio metabolic disorders. Materials and Methods: The current study was performed after the institutional ethical approval. Fifty-two healthy but, obese volunteers aged 17-25 years with BMI ?25.0 were included. Salivary cortisol level was estimated by ELISA. Salivary ?-amylase was measured by kinetic enzyme assay. Data was expressed as Mean ± SD.  The association between anthropometric parameters with salivary cortisol and salivary amylase was done by Pearson correlation test. p value< 0.05 was considered statistically significant. Results: Salivary cortisol in male and female subjects did not show significant correlation (p>0.05) with anthropometric parameters except BMI. Similarly, salivary amylase did not show significant correlation (p>0.05) with Waist-to-height ratio (WHtR), A body shape index (ABSI), Body Round Index (BRI) and Physical Fitness Index (PFI).  The correlation of Waist to hip ratio (WHR) was found to be significantly correlated (p=0.01) with salivary amylase level whereas, the BMI and Body fat % was negatively correlated with salivary amylase level. Conclusion: The newly proposed anthropometric parameters such as WHtR, ABSI, BRI, and PFI did not proved as ideal parameters for early prediction of cardio metabolic disorders in both genders.