Circulatory T-cadherin is a potential biomarker for atherosclerosis
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Published:2022-07-03
Issue:3
Volume:42
Page:417-421
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ISSN:0970-2067
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Container-title:Biomedicine
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language:
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Short-container-title:Biomedicine
Author:
Mohd Danish Khan ,Mohammad Kaleem Ahmad ,Roshan Alam ,Fahad Khan ,Mohammad Mustufa Khan
Abstract
T-cadherin, a special member of cadherin family, expresses with blood circulation involving the heart i.e. CVS. Cadherin is connected with the healthy conditions of an individual and normal functioning of cardio-vascular metabolism. T-cadherin is mainly associated with blood vascular system of human. Previous studies analysed this cadherin been unexpressed within the fat storing tissues i.e. adipose tissue of peri-aortic and peri-coronary, it is present within endothelium as well as in vascularized smooth muscular cells which includes the area nearby coronary vessels and aorta. The area and site of this cadherin is attention-grabbing because it particularly related to atherosclerosis and cardiovascular disease (CVD). T-cadherin - a protein acting as the receptor for low density lipoproteins (LDL). It may act as a special biomarker for atherosclerosis. Previous studies on T-cadherin showed that it has cardio-protective role. Furthermore, research is essential to enumerate the cardio-protective function of T-cadherin. It can be an important therapeutic target in developing new medicine to decrease incident of heart disease and its complications.
Publisher
Indian Association of Biomedical Scientists
Subject
General Biochemistry, Genetics and Molecular Biology,General Medicine
Reference36 articles.
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