β hydroxybutyrate levels in serum and cerebrospinal fluid under ketone body metabolism in rats

Author:

WANG Xiaomeng12,LIU Qi1,ZHOU Jian3,WU Xiuhua1,ZHU Qingan1

Affiliation:

1. Department of Spinal Surgery, Nanfang Hospital, Southern Medical University, Guangzhou, P.R. China

2. Department of Spinal Surgery, Longyan First Hospital, Fujian, P.R.China

3. Department of Spinal Surgery, Nanchang Hongdu Hospital of TCM, Jiangxi, P.R.China

Publisher

Japanese Association for Laboratory Animal Science

Subject

General Veterinary,General Biochemistry, Genetics and Molecular Biology,Animal Science and Zoology,General Medicine

Reference22 articles.

1. 1. Colombo M., Kruhoeffer M., Gregersen S., Agger A., Jeppesen P., Oerntoft T., and Hermansen K. 2006. Energy restriction prevents the development of type 2 diabetes in Zucker diabetic fatty rats: coordinated patterns of gene expression for energy metabolism in insulin-sensitive tissues and pancreatic islets determined by oligonucleotide microarray analysis. Metabolism 55: 43–52.

2. 2. de Assis A.M., da Silva J.S., Rech A., Longoni A., Nonose Y., Repond C., de Bittencourt Pasquali M.A., Moreira J.C., Souza D.O., and Pellerin L. 2016. Cerebral ketone body oxidation is facilitated by a high fat diet enriched with advanced glycation end products in normal and diabetic rats. Front. Neurosci. 10: 509.

3. 3. Douris N., Melman T., Pecherer J.M., Pissios P., Flier J.S., Cantley L.C., Locasale J.W., and Maratos-Flier E. 2015. Adaptive changes in amino acid metabolism permit normal longevity in mice consuming a low-carbohydrate ketogenic diet. Biochim. Biophys. Acta 1852: 2056–2065.

4. 4. Hartman A.L., Rubenstein J.E., and Kossoff E.H. 2013. Intermittent fasting: a “new” historical strategy for controlling seizures? Epilepsy Res. 104: 275–279.

5. 5. Holland A.M., Kephart W.C., Mumford P.W., Mobley C.B., Lowery R.P., Shake J.J., Patel R.K., Healy J.C., McCullough D.J., Kluess H.A., Huggins K.W., Kavazis A.N., Wilson J.M., and Roberts M.D. 2016. Effects of a ketogenic diet on adipose tissue, liver, and serum biomarkers in sedentary rats and rats that exercised via resisted voluntary wheel running. Am. J. Physiol. Regul. Integr. Comp. Physiol. 311: R337–R351.

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