A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains-Reference-Cited by-同舟云学术

A 3-Mbp fragment on rat chromosome 1 affects susceptibility both to stroke and kidney injury under salt loading in the stroke-prone spontaneously hypertensive rat: a genetic approach using multiple congenic strains

Published:2022 Issue:3 Volume:71 Page:368-375
ISSN:1341-1357
Container-title:Experimental Animals
language:en
Short-container-title:Exp. Anim.

Author:

Wang Mei¹,Ohara Hiroki¹,Egawa Masahiro²,Fukunaga Shohei²,Matsuo Hiroyuki¹,Ge Zhi-Ru³,Nabika Toru¹

Affiliation:

1. Department of Functional Pathology, Faculty of Medicine, Shimane University, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan

2. Division of Nephrology, Shimane University Hospital, 89-1 Enya-cho, Izumo, Shimane 693-8501, Japan

3. Department of Cardiology, Shanghai Gongli Hospital, Second Military Medical University, 207 Juye Road, Pudong, Shanghai 200135, P.R. China

Publisher

Japanese Association for Laboratory Animal Science

Subject

General Veterinary,General Biochemistry, Genetics and Molecular Biology,Animal Science and Zoology,General Medicine

Link

https://www.jstage.jst.go.jp/article/expanim/71/3/71_21-0189/_pdf

Reference22 articles.

1. 1. Yamori Y, Horie R, Handa H, Sato M, Fukase M. Pathogenetic similarity of strokes in stroke-prone spontaneously hypertensive rats and humans. Stroke. 1976; 7: 46–53.

2. 2. Nabika T, Ohara H, Kato N, Isomura M. The stroke-prone spontaneously hypertensive rat: still a useful model for post-GWAS genetic studies? Hypertens Res. 2012; 35: 477–484.

3. 3. Gandolgor TA, Ohara H, Cui ZH, Hirashima T, Ogawa T, Saar K, et al.　Two genomic regions of chromosomes 1 and 18 explain most of the stroke susceptibility under salt loading in stroke-prone spontaneously hypertensive rat/Izm. Hypertension. 2013; 62: 55–61.

4. 4. Niiya K, Ohara H, Isono M, Sheikh AM, Matsuo H, Fujikawa K, et al.　Further dissection of QTLs for salt-induced stroke and identification of candidate genes in the stroke-prone spontaneously hypertensive rat. Sci Rep. 2018; 8: 9403.

5. 5. Blezer EL, Schurink M, Nicolay K, Bär PR, Jansen GH, Koomans HA, et al.　Proteinuria precedes cerebral edema in stroke-prone rats: a magnetic resonance imaging study. Stroke. 1998; 29: 167–174.

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1. Genotypes of Stim1 and the proximal region on chromosome 1 exert opposite effects on stroke susceptibility in stroke-prone spontaneously hypertensive rat;Journal of Hypertension;2023-09-14