Minimum environmental enrichment is effective in activating antitumor immunity to transplanted tumor cells in mice

Author:

Takai Daisaku1,Abe Akiko2,Miura Heita2,Tanaka Satoshi1,Komura Jun-ichiro1

Affiliation:

1. Department of Radiobiology, Institute for Environmental Sciences, 2-121 Hacchazawa, Takahoko, Rokkasho, Aomori 039-3213, Japan

2. JAC Co. ltd., 1-2-7 Higashiyama, Meguro, Tokyo 153-0043, Japan

Publisher

Japanese Association for Laboratory Animal Science

Subject

General Veterinary,General Biochemistry, Genetics and Molecular Biology,Animal Science and Zoology,General Medicine

Reference37 articles.

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2. 2. Arranz L., De Castro N.M., Baeza I., Maté I., Viveros M.P. and De la Fuente M. 2010. Environmental enrichment improves age-related immune system impairment: long-term exposure since adulthood increases life span in mice. Rejuvenation Res. 13: 415–428.

3. 3. Benaroya-Milshtein N., Hollander N., Apter A., Kukulansky T., Raz N., Wilf A., Yaniv I. and Pick C.G. 2004. Environmental enrichment in mice decreases anxiety, attenuates stress responses and enhances natural killer cell activity. Eur. J. Neurosci. 20: 1341–1347.

4. 4. Benaroya-Milshtein N., Apter A., Yaniv I., Kukulansky T., Raz N., Haberman Y., Halpert H., Pick C.G. and Hollander N. 2007. Environmental enrichment augments the efficacy of idiotype vaccination for B-cell lymphoma. J. Immunother. 30: 517–522.

5. 5. Birkeland S.A., Storm H.H., Lamm L.U., Barlow L., Blohmé I., Forsberg B., Eklund B., Fjeldborg O., Friedberg M., Frödin L., Glattre E., Halvorsen S., Holm N.V., Jakobsen A., Jorgensen H.E., Ladefoged J., Lindholm T., Lundgren G. and Pukkala E. 1995. Cancer risk after renal transplantation in the Nordic countries, 1964-1986. Int. J. Cancer 60: 183–189.

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