Establishment of a novel experimental system using single cell-derived pleomorphic rhabdomyosarcoma cell lines expressing K-RasG12V and deficient in p53
Author:
Affiliation:
1. Department of Animal Functional Genomics of Advanced Science Research Promotion Center, Organization for Research Initiative and Promotion at Mie University, 2-174 Edobashi, Tsu, Mie 514-8507, Japan
Publisher
Japanese Association for Laboratory Animal Science
Subject
General Veterinary,General Biochemistry, Genetics and Molecular Biology,Animal Science and Zoology,General Medicine
Link
https://www.jstage.jst.go.jp/article/expanim/72/4/72_22-0177/_pdf
Reference32 articles.
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2. 2. Kashi VP, Hatley ME, Galindo RL. Probing for a deeper understanding of rhabdomyosarcoma: insights from complementary model systems. Nat Rev Cancer. 2015; 15: 426–439.
3. 3. Feroce F, Cantile M, Aquino G, Collina F, Scognamiglio G, Castaldo L, et al. Molecular characterization of a bladder pleomorphic rhabdomyosarcoma in an adult patient. Pathol Res Pract. 2020; 216: 153033.
4. 4. Furlong MA, Mentzel T, Fanburg-Smith JC. Pleomorphic rhabdomyosarcoma in adults: a clinicopathologic study of 38 cases with emphasis on morphologic variants and recent skeletal muscle-specific markers. Mod Pathol. 2001; 14: 595–603.
5. 5. Tsumura H, Yoshida T, Saito H, Imanaka-Yoshida K, Suzuki N. Cooperation of oncogenic K-ras and p53 deficiency in pleomorphic rhabdomyosarcoma development in adult mice. Oncogene. 2006; 25: 7673–7679.
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