Features of the application and evaluation of urgent blood pressure monitoring at the pre-hospital stage

Abstract

The purpose of the study. Search for criteria for objectifying the safety of emergency treatment of hypertension syndrome at the outpatient stage of emergency medical care.Tasks: 1) еvaluate the possibility of hardware monitoring of blood pressure at the pre-hospital stage of emergency care; 2) select indicators that allow you to objectively assess the safety of emergency antihypertensive therapy with various two-component drug combinations; 3) the use of urgent blood pressure monitoring to demonstrate the differences between the safety of combinations of captopril with furosemide, moxonidine with furosemide, moxonidine with nifedipine.Materials and methods. At the prehospital stage, blood pressure monitoring was carried out during the day simultaneously with taking a number of combinations of antihypertensive drugs (captopril and furosemide, moxonidine and furosemide, moxonidine and nifedipine). In the absence of intolerance to any of the studied drugs, the choice of drugs was carried out by fixed randomization using a table of random numbers. A total of 91 patients were included in the study, in whom the results of an instrumental study were analyzed against the background of drug therapy.Results. To assess the effectiveness and safety of antihypertensive treatment, the protocol for analyzing primary data was modified, new highly informative quantitative criteria for assessing the effect of various drug combinations on the temporal dynamics of blood pressure were developed.Conclusion. The proposed research methodology allows documenting the course of emergency therapy and can be offered for use during outpatient treatment