Affiliation:
1. Research Institute for Complex Problems of Cardiovascular Diseases
Abstract
The analysis of the literature in the main search scientific systems was carried out to identify the current means of cerebroprotection. The assessment is given both to the familiar methods that have become «traditional» for cardiac surgery (hypothermia, etc.) and pharmacological approaches that are less common in clinical practice: the use of melatonin, ketamine. The characteristics of some drugs that are promising for solving this problem are also given.
Publisher
FSBEI HE I.P. Pavlov SPbSMU MOH Russia
Subject
Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine,Emergency Medicine
Reference50 articles.
1. Ivanova S. A., Losenkov I. S., Bokhan N. A. Role of glycogen synthase kinase-3 in the pathogenesis of mental disorders. Journal of Neurology and Psychiatry named after Korsakov, 2014, vol. 114, no 6, pp. 93‑100. (In Russ.)
2. Ivkin А. А., Grigoriev E. V., Tsepokina А. V. et al. Postoperative delirium in children in undergoing treatment of congenital septal heart defects. Bulletin of anesthesiology and resuscitation, 2021, vol. 18, no. 2, pp. 62-68. (In Russ.) Doi: 10.21292/2078-5658-2021-18-2-62-68.
3. Ivkin A. A., Borisenko D. V., Tsepokina A. V. et al. Refusal of erythrocyte mass to fill the heart-lung machine as the basis for perioperative prevention of cerebral damage in children during cardiac surgery. Anesthesiology and resuscitation, 2021, no. 4, pp. 54-61. (In Russ.) Doi: 10.17116/anaesthesiology202104154.
4. Koval’chuk V. V., Zueva I. B., Nesterin K. V. et al. The use of citoflavin in neonatology and pediatrics as a factor improving therapeutic efficacy in patients with central nervous system lesions of various etiology. Journal of Neurology and Psychiatry named after S. S. Korsakov, 2018, vol. 118, no, 5‑2, pp. 46‑50. (In Russ.) Doi:10.17116/jnevro20181185246.
5. Kuznik BI, Havinson VH, Lin’kova NS, et al. Alarmin1 (hmgb1) and age pathology. Epigenetic mechanisms of regulation. Uspekhi fiziologicheskih nauk [Advances in the physiological sciences]. 2017;48(4):40-55. (In Russ.)