Optical noninvasive diagnostics of the functional state of microcirculatory bed in patients with disorders of peripheral haemodynamics

Author:

Zharkikh E. V.1,Makovik I. N.1,Potapova E. V.1,Dremin V. V.1,Zherebtsov E. A.2,Zherebtsova A. I.1,Dunaev A. V.1,Sidorov V. V.3,Krupatkin A. I.4

Affiliation:

1. Federal State Budgetary Educational Institution of Higher Education «Orel State University named after I. S. Turgenev»

2. Federal State Budgetary Educational Institution of Higher Education «Orel State University named after I. S. Turgenev»; Aston University

3. SPE «LAZMA» Ltd., Moscow

4. Federal State Budgetary Educational Institution of Higher Education «N. N. Priorov National Medical research center of traumatology and orthopaedics» of Ministry of Healthcare of the Russion Federation

Abstract

The possibilities and prospects of optical non-invasive diagnostic technologies for detecting and assessing the severity of microcirculatory and metabolic disorders in rheumatic diseases and diabetes mellitus were assessed. Experimental studies were conducted with the participation of 137 conditionally healthy volunteers and 147 patients with mentioned diseases (77 patients with rheumatic diseases and 70 patients with diabetes). It is shown that the application of laser Doppler flowmetry, fluorescence spectroscopy and diffuse reflectance spectroscopy is of great diagnostic importance for identifying emerging disorders, and these methods can be used as additional diagnostic methods in the arsenal of a practicing physician in the field of rheumatology and endocrinology.

Publisher

FSBEI HE I.P. Pavlov SPbSMU MOH Russia

Subject

General Medicine

Reference46 articles.

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