Affiliation:
1. Almazov National Medical Research Centre
2. Railways clinical hospital of OJSC Russian Railways
Abstract
INTRODUCTION. The problem of preventing massive pulmonary thromboembolism and post-thrombotic syndrome in deep vein thrombosis has been studied for a long period. The introduction of new treatments for deep vein thrombosis requires a detailed comparison of their effectiveness.The OBJECTIVE of this work was a comparative analysis of ligation of the superficial femoral vein and regional thrombolytic therapy.MATERIAL AND METHODS. A retrospective multicenter study involving 30 patients with femoproplite thrombosis, who had received catheter-directed thrombolysis or ligation of the superficial femoral vein, was performed. The investigated patients underwent inpatient treatment.RESULTS. The data on the effectiveness of both methods in preventing pulmonary thromboembolism were obtained. When comparing both groups, we revealed a statistically significant difference in the frequency of the development of PTS and the severity of its development in 1 year after treatment. With ligation vein, 73.3 and 6.7% in the thrombolysis group (p=0.0005).CONCLUSION. Regional thrombolysis was an effective treatment for deep vein thrombosis and prevention of PTS.The authors declare no conflict of interest.The authors confirm that they respect the rights of the people participated in the study, including obtaining informed consent when it is necessary, and the rules of treatment of animals when they are used in the study. Author Guidelines contains the detailed information.
Publisher
FSBEI HE I.P. Pavlov SPbSMU MOH Russia