The choice of lightweight synthetic material for replacement of the abdominal wall (experimental study)

Abstract

The objective is to determine the optimal synthetic material for endoprosthetics of the abdominal wall.Material and methods. The experiments were conducted on 50 rabbits of the Chinchilla breed, which were divided into 2 groups of 25 individuals in the each group. In the first group, a lightweight polypropylene endoprosthesis with filament diameter of 90 microns was implanted at the aponeurosis of the anterior abdominal wall, and in the second group – a super-lightweight polypropylene polyvinylidene fluoride endoprothesis with filament diameter of 70 microns. We performed morphometric and histological study of reactive changes in the tissue surrounding the implanted endoprosthesis.Results. In the animals of the second group, the inflammatory response to the implanted prosthesis was on the 3rd day of the experiment lower by 1.3 times, on the 7th day – 1.2 times, on the 10th – 1.1 times; fibroblastic response on the contrary increased 1.2, 1.12, 1.16 times on the same days.Conclusion. When choosing a lightweight synthetic material for hernioplasty, the preference should be given to the super-lightweight polypropylenepolyvinylidene fluoride endoprosthesis.