Characterization of Secondary Metabolites from Mycelial Cultures of Black Morel Mushroom Morchella importuna (Ascomycota)

Author:

Zhou Jinquan,Yang Cailing,Meng Qingfeng,Fu Shaobin 

Abstract

Species of the genus <i>Morchella</i> are highly prized worldwide for their excellent flavor and high medicinal value. In recent years, artificial cultivations of medicinal fungi with many advantages have elicited great interest as a promising alternative to produce certain valuable metabolites. Therefore, the secondary metabolites of fermented <i>M. importuna</i> belonging to the black morel clade isolated from China were investigated. The strain was cultured in a fermentation tank in PDB liquid medium by two-step method. The mycelia and fermentation broth were extracted by ethyl acetate. The secondary metabolites were separated and purified by repeated silica gel column chromatography. Structures of compounds were determined by NMR data and references. One new natural compound <b>(1)</b> and six known compounds <b>(2-7)</b> were obtained. Compounds<b> 1, 2, 4,</b> and<b> 5</b> were first isolated from genus <i>Morchella</i> and compounds<b> 3, 6,</b> and<b> 7</b> are first isolated from species <i>M. importuna</i>.

Publisher

Begell House

Subject

Drug Discovery,Pharmacology,Applied Microbiology and Biotechnology

Reference39 articles.

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