CROSS-SCALE MODELING OF LIQUID FLOWS IN HUMAN BODIES

Abstract

Multiple modeling approaches to liquid flows in human bodies are reviewed. They span from the macroscale size > 1 mm to the nanoscale size only on the 1 nm scale. They can respectively model the flows of the blood in large arteries, small arteries, arterioles, and capillaries; and the flows of water through the nanopores of the capillary wall, the cellular membrane, and the cellular connexon. They are respectively the macroscale continuum flow modeling, the mesoscale one-dimensional continuum flow modeling, the microscale dissipative particle dynamics method, the macro-nano multiscale flow modeling, and the nanoscale flow modeling. Integrating these approaches together can give comprehensive simulations of liquid flows in human bodies.