1. U.S. Food and Drug Administration, Bureau of Foods. OECD 422: Combined Repeated Dose Toxicity Study with Toxicological Principles for the Safety Assessment of Direct the Reproduction/Developmental Toxicity Screening Test Food Additives and Color Additives Used in Foods, U.S. Food (Original Guideline, adopted March 22, 1996), OECD, and Drug Administration, Washington, DC, 1982. Paris, France, 1996.
2. U.S. Food and Drug Administration, Center for Food Safety 20. Organization for Economic Cooperation and Development. and Applied Nutrition. Toxicological principles for the Safety OECD 414: Prenatal Developmental Toxicity Study Assessment of Direct Food Additives and Color Additives (Updated Guideline, adopted January 22, 2001), OECD, Used in Foods, "Redbook II" (draft), U.S. Food and Drug Paris, France, 2001. Administration, Washington, DC, 1993. 21. Organization for Economic Cooperation and Development.
3. U.S. Food andDrug Administration.International Conference OECD 416: Two-Generation Reproduction Toxicity Study on Harmonisation; Guideline on Detection of Toxicity to (Updated Guideline, adopted January 22, 2001), OECD Paris, Reproduction for Medicinal Products, Federal Register, Part 2001. IX, 59(183), 48746-48752, 1994. 22. International Conference on Harmonization of Technical
4. U.S. Food andDrug Administration.International Conference Requirements of Pharmaceuticals for Human Use. Detection on Harmonisation; Guideline on Detection of Toxicity to of Toxicity to Reproduction of Medicinal Products, Federal Reproduction for Medicinal Products; Addendum on Toxicity Register, 59(1831), 48746-48752, 1994. toMale Fertility, Federal Register, April 5, 1996, 61(67), 1996.