Affiliation:
1. UNIVERSITY OF HEALTH SCIENCES, ANKARA DIŞKAPI YILDIRIM BEYAZIT HEALTH RESEARCH CENTER, DEPARTMENT OF INTERNAL MEDICINE
2. UNIVERSITY OF HEALTH SCIENCES, ANKARA DIŞKAPI YILDIRIM BEYAZIT HEALTH RESEARCH CENTER, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF CARDIOLOGY
Abstract
Aim: Familial Mediterranean Fever (FMF), is a chronic auto-inflammatory disease characterized with recurrent attacks. In between attacks, subclinical inflammation persists which results in increased risk of atherosclerosis. Epicardial adipose tissue is a novel cardiometabolic risk factor which predicts the risk of atherosclerosis.
The aim of this study was to measure the epicardial adipose tissue thickness (EATT) and to evaluate the risk of subclinical atherosclerosis in patients with FMF.
Materials and Methods: 18 years old and older FMF patients diagnosed according to Tel-Hashomer criteria and age and sex matched healthy individuals were recruited for this cross-sectional study. Disease characteristics, gene mutations, erythrocyte sedimentation rate, C-reactive protein, serum amyloid-A, fibrinogen, lipid levels and complete blood counts were recorded at the time of inclusion. EATT was measured by a two-dimensional transthoracic echocardiography. A p value
Publisher
Medical Journal of Ankara Training and Research Hospital
Subject
General Earth and Planetary Sciences,General Environmental Science