Evaluation of FSH, LH ,Testosterone , Prolactine, TSH and T4 hormones levels in different subgroups of infertile males.

Abstract

Gonadotropins (FSH, LH) and testosterone are the prime regulators of germ cell development. Abnormal spermatogenesis is often associated with altered serum gonadotropins and testosterone. the potential relationship between other hormones, including thyroid hormones, and semen quality are still not completely understood. Thus in the present study an attempt has been made to report the degree of  associations between thyroid hormones and semen quality. FSH, LH .T.  PRL.T4 and TSH.hormones levels were estimated in 39 infertile men of whom 5 were azoospermia, 13 were oligozoospermic, 21 were with asthenzoospermia . Results showed statistically significant  differences(P≤ 0.05) in the mean FSH, Testosteron (T.), PRL. And T4. Levels in all the infertile males studied when compared with the fertile controls (n=39). However, there is no significant difference in the mean levels of LH and TSH between the infertile and fertile men. Present study found that though men with abnormal semen profile had slightly higher in T4 concentrations in  asthenozoospermia group  as compared to those with normal semen profile. This study also show positive correlation between T4 and T. ( R2=0.408) and negative correlation between T4 and FSH was (R2=-0.515) ,T4 and LH was (R2=-0.345).