Exploring the effect and mechanism of Aloin A against cancer cachexia-induced muscle atrophy via network pharmacology, molecular docking, molecular dynamics and experimental validation

Author:

Dawuti Awaguli12,Ma Lisha1,An Xueyan1,Guan Jiawei1,Zhou Changdong1,He Linyun1,Xu Yue3,Han Bo1,Abulizi Abudumijiti14

Affiliation:

1. Key Laboratory of Xinjiang Phytomedicine Resource and Utilization, Ministry of Education, College of Pharmacy, Shihezi University, Shihezi 832002, China

2. State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China

3. Division of Pharmaceutics and Pharmacology, College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA

4. State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100191, China

Publisher

Impact Journals, LLC

Subject

Cell Biology,Aging

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