Rewiring of IGF1 secretion and enhanced IGF1R signaling induced by co-chaperone carboxyl-terminus of Hsp70 interacting protein in adipose-derived stem cells provide augmented cardioprotection in aging-hypertensive rats

Author:

Barik Parthasarathi1,Kuo Wei-Wen2,Kuo Chia-Hua3,Hsieh Dennis Jine-Yuan45,Day Cecilia Hsuan6,Daddam Jayasimharayalu7,Chen Michael Yu-Chih8,Padma V. Vijaya9,Shibu Marthandam Asokan9,Huang Chih-Yang17101112

Affiliation:

1. Graduate Institute of Basic Medical Science, China Medical University, Taichung, Taiwan

2. Department of Biological Science and Technology, China Medical University, Taichung, Taiwan

3. Laboratory of Exercise Biochemistry, University of Taipei, Taipei, Taiwan

4. School of Medical Laboratory and Biotechnology, Chung Shan Medical University, Taichung, Taiwan

5. Clinical Laboratory, Chung Shan Medical University Hospital, Taichung, Taiwan

6. Department of Nursing, Mei Ho University, Pingtung, Taiwan

7. Cardiovascular and Mitochondrial Related Disease Research Center, Hualien Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, Hualien, Taiwan

8. Department of Cardiology, Buddhist Tzu Chi General Hospital, Hualien, Taiwan

9. Department of Biotechnology, Bharathiar University, Coimbatore, India

10. Department of Medical Research, China Medical University Hospital, China Medical University, Taichung, Taiwan

11. Department of Biotechnology, Asia University, Taichung, Taiwan

12. Center of General Education, Buddhist Tzu Chi Medical Foundation, Tzu Chi University of Science and Technology, Hualien, Taiwan

Publisher

Impact Journals, LLC

Subject

Cell Biology,Aging

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