Targeting mitochondrial dysfunction using methylene blue or mitoquinone to improve skeletal aging

Author:

Poudel Sher Bahadur1,Frikha-Benayed Dorra2,Ruff Ryan R.3,Yildirim Gozde1,Dixit Manisha1,Korstanje Ron4,Robinson Laura4,Miller Richard A.5,Harrison David E.6,Strong John R.78,Schaffler Mitchell B.2,Yakar Shoshana1

Affiliation:

1. Department of Molecular Pathobiology, David B. Kriser Dental Center, New York University College of Dentistry, New York, NY 10010-4086, USA

2. Department of Biomedical Engineering, City College of New York, New York, NY 10031, USA

3. Department of Epidemiology and Health Promotion, David B. Kriser Dental Center, New York University College of Dentistry, New York, NY 10010-4086, USA

4. Jackson Aging Center, Nathan Shock Center for Excellence in the Basic Biology of Aging, The Jackson’s Laboratories, Aging Center, Bar Harbor, ME 04609, USA

5. Department of Pathology and Geriatrics Center, University of Michigan, Ann Arbor, MI 48109, USA

6. The Jackson Laboratory, Bar Harbor, ME 04609, USA

7. Geriatric Research, Education and Clinical Center and Research Service, South Texas Veterans Health Care System, San Antonio, TX 78229, USA

8. Department of Pharmacology, Barshop Institute for Longevity and Aging Studies, The University of Texas Health Science Center, San Antonio, TX 78229, USA

Publisher

Impact Journals, LLC

Reference55 articles.

1. Oxidative Stress and Osteoporosis.;Carlson;J Bone Joint Surg Am,2021

2. Oral supplementation with antioxidant agents containing alpha lipoic acid: effects on postmenopausal bone mass.;Torella;Clin Exp Obstet Gynecol,2012

3. Potential role of the antioxidant N-acetylcysteine in slowing bone resorption in early post-menopausal women: a pilot study.;Nicholson;Transl Res,2007

4. Antioxidant status in patients with osteoporosis: a controlled study.;Serter;Joint Bone Spine,2009

5. Oxidative Stress and Natural Antioxidants in Osteoporosis: Novel Preventive and Therapeutic Approaches.;Brandi;Antioxidants (Basel),2023

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