PERK activation by SB202190 ameliorates amyloidogenesis via the TFEB-induced autophagy-lysosomal pathway

Author:

Do Mihyang1,Park Jeongmin1,Chen Yubing1,Rah So-Young2,Nghiem Thu-Hang Thi1,Gong Jeong Heon1,Ju Seong-A1,Kim Byung-Sam1,Yu Rina3,Park Jeong Woo1,Ryter Stefan W.4,Surh Young-Joon56,Kim Uh-Hyun2,Joe Yeonsoo1,Chung Hun Taeg1

Affiliation:

1. Department of Biological Sciences, University of Ulsan, Ulsan 44610, Republic of Korea

2. National Creative Research Laboratory for Ca2+ Signaling Network, Chonbuk National University Medical School, Jeonju 54907, Republic of Korea

3. Department of Food Science and Nutrition, University of Ulsan, Ulsan 44610, Republic of Korea

4. Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA

5. Department of Molecular Medicine and Biopharmaceutical Sciences, Graduate School of Convergence Science and Technology, Seoul National University, Seoul 08826, Republic of Korea

6. Cancer Research Institute, Seoul National University, Seoul 03080, Republic of Korea

Publisher

Impact Journals, LLC

Subject

Cell Biology,Aging

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