Selective ATM inhibition augments radiation-induced inflammatory signaling and cancer cell death
Author:
Affiliation:
1. Translational Innovation Platform Oncology and Immuno-Oncology, EMD Serono, Billerica, MA 01821, USA
2. Translational Innovation Platform Oncology and Immuno-Oncology, The Healthcare Business of Merck KGaA, Darmstadt, Hesse, Germany
Publisher
Impact Journals, LLC
Subject
Cell Biology,Aging
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4. The DNA damage response: making it safe to play with knives.;Elledge;Mol Cell,2010
5. The ATM protein kinase: regulating the cellular response to genotoxic stress, and more.;Ziv;Nat Rev Mol Cell Biol,2013
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1. Synergistic inhibition of APE1 redox activity and ATM activation sensitizes osteosarcoma cells to ionizing radiation by inducing ferroptosis;2024-01-31
2. ATM inhibition augments type I interferon response and antitumor T-cell immunity when combined with radiation therapy in murine tumor models;Journal for ImmunoTherapy of Cancer;2023-09
3. Targeting ATM and ATR for cancer therapeutics: Inhibitors in clinic;Drug Discovery Today;2023-08
4. The mechanism and clinical application of DNA damage repair inhibitors combined with immune checkpoint inhibitors in the treatment of urologic cancer;Frontiers in Cell and Developmental Biology;2023-05-25
5. ATM Inhibition-Induced ISG15/IFI27/OASL Is Correlated with Immunotherapy Response and Inflamed Immunophenotype;Cells;2023-04-30
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