Epidermal growth factor receptor mutation mediates cross-resistance to panitumumab and cetuximab in gastrointestinal cancer

Author:

Braig Friederike1,März Manuela1,Schieferdecker Aneta1,Schulte Alexander2,Voigt Mareike1,Stein Alexander1,Grob Tobias3,Alawi Malik4,Indenbirken Daniela5,Kriegs Malte6,Engel Erik7,Vanhoefer Udo8,Grundhoff Adam5,Loges Sonja19,Riecken Kristoffer10,Fehse Boris10,Bokemeyer Carsten1,Binder Mascha1

Affiliation:

1. Department of Oncology and Hematology, BMT with section Pneumology, Hubertus Wald Tumorzentrum / UCCH, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

2. Department of Neurosurgery, Laboratory for Brain Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

3. Department of Pathology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

4. Bioinformatics Service Facility, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

5. Heinrich-Pette-Institute, Leibniz-Institute for Experimental Virology (HPI), Hamburg, Germany

6. Radiation Biology and Radio-Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

7. Hämatologisch-onkologische Praxis Altona (HOPA), Hamburg, Germany

8. Marienkrankenhaus, Zentrum für Innere Medizin, Hamburg, Germany

9. Institute for Tumor Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

10. Research Department Cell and Gene Therapy, Department of Stem Cell Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

Publisher

Impact Journals, LLC

Subject

Oncology

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