Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells

Author:

Arai Wataru12,Konno Takumi2,Kohno Takayuki2,Kodera Yuki3,Tsujiwaki Mitsuhiro4,Shindo Yuma12,Chiba Hirofumi3,Miyajima Masahiro1,Sakuma Yuji5,Watanabe Atsushi1,Kojima Takashi2

Affiliation:

1. Department of Thoracic Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan

2. Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

3. Department of Respiratory Medicine and Allergology, Sapporo Medical University School of Medicine, Sapporo, Japan

4. Department of Pathology, Sapporo Medical University School of Medicine, Sapporo, Japan

5. Department of Molecular Medicine, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan

Publisher

Impact Journals, LLC

Subject

Oncology

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