Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma-Reference-Cited by-同舟云学术

Functional, chemical genomic, and super-enhancer screening identify sensitivity to cyclin D1/CDK4 pathway inhibition in Ewing sarcoma

Published:2015-08-18 Issue:30 Volume:6 Page:30178-30193
ISSN:1949-2553
Container-title:Oncotarget
language:en
Short-container-title:Oncotarget

Author:

Kennedy Alyssa L.¹²,Vallurupalli Mounica¹³,Chen Liying¹,Crompton Brian¹,Cowley Glenn⁴,Vazquez Francisca⁴,Weir Barbara A.⁴,Tsherniak Aviad⁴,Parasuraman Sudha⁵,Kim Sunkyu⁵,Alexe Gabriela¹⁴⁶,Stegmaier Kimberly¹⁴

Affiliation:

1. Department of Pediatric Oncology, Dana-Farber Cancer Institute and Boston Children's Hospital, Boston, Massachusetts, USA

2. Boston Combined Residency Program in Pediatrics, Boston, Massachusetts, USA

3. Department of Internal Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA

4. Broad Institute, Cambridge, Massachusetts, USA

5. Novartis Institute for Biomedical Research, Cambridge, Massachusetts, USA

6. Bioinformatics Graduate Program, Boston University, Boston, Massachusetts, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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1. EWS-WT1 fusion isoforms establish oncogenic programs and therapeutic vulnerabilities in desmoplastic small round cell tumors;Nature Communications;2024-08-28

2. Consensus recommendations for systemic therapies in the management of relapsed Ewing sarcoma: A report from the National Ewing Sarcoma Tumor Board;Cancer;2024-08-25

3. EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells;International Journal of Molecular Sciences;2024-08-06

4. Desmoplastic small round cell tumor: from genomics to targets, potential paths to future therapeutics;Frontiers in Cell and Developmental Biology;2024-07-30

5. Emerging therapies in Ewing sarcoma;Current Opinion in Oncology;2024-05-22