Association of high microvessel αvβ3 and low PTEN with poor outcome in stage 3 neuroblastoma: rationale for using first in class dual PI3K/BRD4 inhibitor, SF1126

Author:

Erdreich-Epstein Anat12,Singh Alok R.3,Joshi Shweta3,Vega Francisco M.34,Guo Pinzheng1,Xu Jingying1,Groshen Susan5,Ye Wei5,Millard Melissa1,Campan Mihaela6,Morales Guillermo7,Garlich Joseph R.7,Laird Peter W.689,Seeger Robert C.1,Shimada Hiroyuki2,Durden Donald L.3710

Affiliation:

1. Department of Pediatrics, Children's Hospital Los Angeles and University of Southern California Keck School of Medicine, Los Angeles, California, USA

2. Department of Pathology, Children's Hospital Los Angeles and University of Southern California Keck School of Medicine, Los Angeles, California, USA

3. Department of Pediatrics, Moores Cancer Center, University of California San Diego, California, USA

4. Instituto de Biomedicina de Sevilla, IBiS/HUVR/CSIC/Universidad de Sevilla and Department of Medical Physiology and Biophysics, Universidad de Sevilla, Spain

5. Department of Preventive Medicine, Keck School of Medicine, Los Angeles, California, USA

6. Department of Surgery University of Southern California, Keck School of Medicine, Los Angeles, California, USA

7. SignalRx Pharmaceuticals, San Diego, California, USA

8. USC Epigenome Center, University of Southern California, Keck School of Medicine, Los Angeles, California, USA

9. Current Address: Van Andel Research Institute, Grand Rapids, Michigan, USA

10. Department of Pediatrics, UCSD School of Medicine and Rady Children's Hospital San Diego, California, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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