Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

Author:

Oh Sekyung12,Flynn Ryan A.3,Floor Stephen N.4,Purzner James56,Martin Lance4,Do Brian T.4,Schubert Simone1,Vaka Dedeepya1,Morrissy Sorana78,Li Yisu9,Kool Marcel10,Hovestadt Volker11,Jones David T.W.10,Northcott Paul A.10,Risch Thomas12,Warnatz Hans-Jörg12,Yaspo Marie-Laure12,Adams Christopher M.13,Leib Ryan D.13,Breese Marcus14,Marra Marco A.9,Malkin David15,Lichter Peter11,Doudna Jennifer A.4161718,Pfister Stefan M.10,Taylor Michael D.78919,Chang Howard Y.320,Cho Yoon-Jae122122

Affiliation:

1. Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA

2. Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA

3. Program in Epithelial Biology, Stanford University School of Medicine, Stanford, CA, USA

4. Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA

5. Department of Developmental Biology, Stanford University School of Medicine, Stanford, CA, USA

6. Department of Surgery, Division of Neurosurgery, University of Toronto, ON, Canada

7. Developmental and Stem Cell Biology Program, The Hospital for Sick Children, Toronto, ON, Canada

8. Department of Surgery, Division of Neurosurgery and Labatt Brain Tumour Research Centre, The Hospital for Sick Children, Toronto, ON, Canada

9. Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver, BC Canada

10. Division of Pediatric Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany

11. Division of Molecular Genetics, German Cancer Research Center (DKFZ), Heidelberg, Germany

12. Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Berlin, Germany

13. The Vincent Coates Foundation Mass Spectrometry Laboratory, Stanford University, Stanford, CA, USA

14. Cancer Biology Program, Stanford University School of Medicine, Stanford, CA, USA

15. Cancer Genetic Program, The Hospital for Sick Children, Toronto, ON, Canada

16. Department of Chemistry, University of California, Berkeley, CA, USA

17. Physical Biosciences Division, Lawrence Berkeley National Laboratory, Berkeley, CA, USA

18. Howard Hughes Medical Institute, University of California, Berkeley, CA, USA

19. Department of Laboratory Medicine and Pathobiology, University of Toronto, ON, Canada

20. Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA, USA

21. Papé Family Pediatric Research Institute, Department of Pediatrics, Oregon Health and Science University, Portland, OR, USA

22. Knight Cancer Institute, Oregon Health and Science University, Portland, OR, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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