Development of zebrafish medulloblastoma-like PNET model by TALEN-mediated somatic gene inactivation

Author:

Shim Jaegal1,Choi Jung-Hwa2,Park Moon-Hak3,Kim Hyena3,Kim Jong Hwan4,Kim Seon-Young4,Hong Dongwan5,Kim Sunshin6,Lee Ji Eun7,Kim Cheol-Hee2,Lee Jeong-Soo8910,Bae Young-Ki13

Affiliation:

1. Comparative Biomedicine Research Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea

2. Department of Biology, Chungnam National University, Daejeon, Republic of Korea

3. Tumor Microenviroment Research Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea

4. Genome Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea

5. Clinical Genomic Analysis Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea

6. Precision Medicine Branch, Research Institute, National Cancer Center, Goyang, Republic of Korea

7. Department of Health Sciences and Technology, Samsung Advanced Institute for Health Sciences and Technology, Sungkyunkwan University, Gangnam-gu, Seoul, Republic of Korea

8. Disease Target Structure Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea

9. Convergence Research Center for Dementia DTC, Korea Institute of Science and Technology, Seoul, Republic of Korea

10. Department of Functional Genomics, Korea University of Science and Technology, Daejeon, Republic of Korea

Publisher

Impact Journals, LLC

Subject

Oncology

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