Small-molecule induction of phospho-eIF4E sumoylation and degradation via targeting its phosphorylated serine 209 residue

Author:

Gu Ying123,Zhou Hong12,Gan Yichao12,Zhang Jiawei23,Chen Jianghua12,Gan Xiaoxian34,Li Hongzhi5,Zheng Weiwei12,Meng Zhipeng3,Ma Xiaoxiao3,Wang Xichun3,Xu Xiaohua1,Xu Ganyu3,Lu Xiaoya12,Liang Yun1,Zhang Xuzhao1,Lu Xinliang2,Huang Wendong3,Xu Rongzhen12

Affiliation:

1. Department of Hematology, Key Laboratory of Cancer Prevention and Intervention, China National Ministry of Education, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

2. Cancer Institute, Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China

3. Division of Molecular Diabetes Research, Department of Diabetes and Metabolic Diseases Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA

4. Zhejiang Academy of Medical Sciences, Hangzhou 310012, China

5. Department of Molecular Medicine, Beckman Research Institute, City of Hope National Medical Center, Duarte, CA 91010, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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