Phospholipid profiling identifies acyl chain elongation as a ubiquitous trait and potential target for the treatment of lung squamous cell carcinoma

Author:

Marien Eyra1,Meister Michael23,Muley Thomas23,del Pulgar Teresa Gomez4,Derua Rita5,Spraggins Jeffrey M.6,Van de Plas Raf67,Vanderhoydonc Frank1,Machiels Jelle1,Binda Maria Mercedes8,Dehairs Jonas1,Willette-Brown Jami9,Hu Yinling9,Dienemann Hendrik310,Thomas Michael311,Schnabel Philipp A.312,Caprioli Richard M.6,Lacal Juan Carlos4,Waelkens Etienne5,Swinnen Johannes V.1

Affiliation:

1. KU Leuven - University of Leuven, LKI - Leuven Cancer Institute, Department of Oncology, Laboratory of Lipid Metabolism and Cancer, Leuven, Belgium

2. Thoraxklinik at University Hospital Heidelberg, Translational Research Unit, Heidelberg, Germany

3. TLRC-H - Translational Lung Research Center Heidelberg, Member of The German Center for Lung Research, Heidelberg, Germany

4. Fundación Jiménez Díaz, Division of Translational Oncology, Madrid, Spain

5. KU Leuven - University of Leuven, Department of Cellular and Molecular Medicine, Laboratory of Protein Phosphorylation and Proteomics, Leuven, Belgium

6. Vanderbilt University Medical Center, Department of Biochemistry and Mass Spectrometry Research Center, Nashville, TN, USA

7. Delft University of Technology, Delft Center for Systems and Control, Delft, The Netherlands

8. KU Leuven - University of Leuven, LKI - Leuven Cancer Institute, Department of Oncology, Abdominal Surgical Oncology, Leuven, Belgium

9. National Cancer Institute, Centre for Cancer Research, Cancer and Inflammation Program, Frederick, MD, USA

10. Thoraxklinik at University Hospital Heidelberg, Department of Surgery, Heidelberg, Germany

11. Thoraxklinik at University Hospital Heidelberg, Department of Thoracic Oncology, Heidelberg, Germany

12. University of The Saarland, Institut für Allgemeine und Spezielle Pathologie, Homburg/Saar, Germany

Publisher

Impact Journals, LLC

Subject

Oncology

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