DPYD and UGT1A1 genotyping to predict adverse events during first-line FOLFIRI or FOLFOXIRI plus bevacizumab in metastatic colorectal cancer

Author:

Cremolini Chiara1,Del Re Marzia2,Antoniotti Carlotta1,Lonardi Sara3,Bergamo Francesca3,Loupakis Fotios1,Borelli Beatrice1,Marmorino Federica1,Citi Valentina2,Cortesi Enrico4,Moretto Roberto1,Ronzoni Monica5,Tomasello Gianluca6,Zaniboni Alberto7,Racca Patrizia8,Buonadonna Angela9,Allegrini Giacomo10,Ricci Vincenzo11,Di Donato Samantha12,Zagonel Vittorina3,Boni Luca13,Falcone Alfredo1,Danesi Romano2

Affiliation:

1. Unit of Medical Oncology 2, Azienda Ospedaliera-Universitaria Pisana, University of Pisa, Istituto Toscano Tumori, Pisa, Italy

2. Clinical Pharmacology and Pharmacogenetics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy

3. Oncologia Medica 1, Istituto Oncologico Veneto, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS), Padova, Italy

4. Department of Medical Oncology, Policlinico Umberto I “Sapienza” University of Rome, Roma, Italy

5. Medical Oncology Unit, Ospedale San Raffaele-IRCCS, Milano, Italy

6. ASST di Cremona, Ospedale di Cremona, Cremona, Italy

7. Fondazione Poliambulanza Hospital, Brescia, Italy

8. SSD ColoRectal Unit-Dipartimento di Oncologia, AOU Città della Salute e della Scienza di Torino, Torino, Italy

9. Medical Oncology Unit, CRO-National Cancer Institute, Aviano, Italy

10. Medical Oncology Unit, Presidio Ospedaliero Felice Lotti, Pontedera, Italy

11. Department of Oncology, S. Croce and Carle Teaching Hospital, Cuneo, Italy

12. Medical Oncology Department, Nuovo Ospedale-Santo Stefano, Istituto Toscano Tumori, Prato, Italy

13. Clinical Trial Coordinating Center, AOU Careggi, Istituto Toscano Tumori, Firenze, Italy

Publisher

Impact Journals, LLC

Subject

Oncology

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