Genetic interaction analysis among oncogenesis-related genes revealed novel genes and networks in lung cancer development

Author:

Li Yafang1,Xiao Xiangjun1,Bossé Yohan2,Gorlova Olga3,Gorlov Ivan3,Han Younghun1,Byun Jinyoung1,Leighl Natasha4,Johansen Jakob S.5,Barnett Matt6,Chen Chu6,Goodman Gary7,Cox Angela8,Taylor Fiona8,Woll Penella8,Wichmann H. Erich9,Manz Judith9,Muley Thomas10,Risch Angela111213,Rosenberger Albert14,Han Jiali15,Siminovitch Katherine16,Arnold Susanne M.17,Haura Eric B.18,Bolca Ciprian19,Holcatova Ivana20,Janout Vladimir20,Kontic Milica21,Lissowska Jolanta22,Mukeria Anush23,Ognjanovic Simona24,Orlowski Tadeusz M.25,Scelo Ghislaine26,Swiatkowska Beata27,Zaridze David23,Bakke Per28,Skaug Vidar29,Zienolddiny Shanbeh29,Duell Eric J.30,Butler Lesley M.31,Houlston Richard32,Artigas María Soler3334,Grankvist Kjell35,Johansson Mikael36,Shepherd Frances A.37,Marcus Michael W.38,Brunnström Hans39,Manjer Jonas40,Melander Olle40,Muller David C.41,Overvad Kim42,Trichopoulou Antonia43,Tumino Rosario44,Liu Geoffrey45,Bojesen Stig E.464748,Wu Xifeng49,Le Marchand Loic50,Albanes Demetrios51,Bickeböller Heike14,Aldrich Melinda C.52,Bush William S.53,Tardon Adonina54,Rennert Gad55,Teare M. Dawn56,Field John K.38,Kiemeney Lambertus A.57,Lazarus Philip58,Haugen Aage29,Lam Stephen59,Schabath Matthew B.60,Andrew Angeline S.61,Bertazzi Pier Alberto6263,Pesatori Angela C.63,Christiani David C.64,Caporaso Neil51,Johansson Mattias45,McKay James D.45,Brennan Paul45,Hung Rayjean J.26,Amos Christopher I.65

Affiliation:

1. Baylor College of Medicine, Houston, TX, USA

2. Laval University, Quebec, QC, Canada

3. Department of Biomedical Data Science, Dartmouth College, Hanover, NH, USA

4. University Health Network, The Princess Margaret Cancer Centre, Toronto, CA, USA

5. Department of Oncology, Herlev and Gentofte Hospital, Copenhagen University Hospital, Copenhagen, Denmark

6. Fred Hutchinson Cancer Research Center, Seattle, WA, USA

7. Swedish Medical Group, Seattle, WA, USA

8. Department of Oncology, University of Sheffield, Sheffield, UK

9. Research Unit of Molecular Epidemiology, Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany

10. Thoraxklinik at University Hospital Heidelberg, Translational Lung Research Center Heidelberg (TLRC-H), Heidelberg, Germany

11. Translational Lung Research Center Heidelberg (TLRC-H), Heidelberg, Germany

12. German Center for Lung Research (DKFZ), Heidelberg, Germany

13. University of Salzburg and Cancer Cluster, Salzburg, Austria

14. Department of Genetic Epidemiology, University Medical Center, Georg-August-University Göttingen, Göttingen, Germany

15. Indiana University, Bloomington, IN, USA

16. University of Toronto, Toronto, ON, Canada

17. University of Kentucky, Markey Cancer Center, Lexington, KY, USA

18. Department of Thoracic Oncology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

19. Institute of Pneumology “Marius Nasta”, Bucharest, Romania

20. Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic

21. Clinical Center of Serbia, School of Medicine, University of Belgrade, Belgrade, Serbia

22. M. Sklodowska-Curie Cancer Center, Institute of Oncology, Warsaw, Poland

23. Department of Epidemiology and Prevention, N.N. Blokhin Russian Cancer Research Center, Moscow, Russian Federation

24. International Organization for Cancer Prevention and Research, Belgrade, Serbia

25. Department of Surgery, National Tuberculosis and Lung Diseases Research Institute, Warsaw, Poland

26. International Agency for Research on Cancer, World Health Organization, Lyon, France

27. Nofer Institute of Occupational Medicine, Department of Environmental Epidemiology, Lodz, Poland

28. Department of Clinical Science, University of Bergen, Bergen, Norway

29. National Institute of Occupational Health, Oslo, Norway

30. Unit of Nutrition and Cancer, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain

31. University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA

32. The Institute of Cancer Research, London, UK

33. Department of Health Sciences, Genetic Epidemiology Group, University of Leicester, Leicester, UK

34. National Institute for Health Research (NIHR) Leicester Respiratory Biomedical Research Unit, Glenfield Hospital, Leicester, UK

35. Department of Medical Biosciences, Umeå University, Umeå, Sweden

36. Department of Radiation Sciences, Umeå University, Umeå, Sweden

37. Princess Margaret Cancer Centre, Toronto, ON, Canada

38. Institute of Translational Medicine, University of Liverpool, Liverpool, UK

39. Department of Pathology, Lund University, Lund, Sweden

40. Faculty of Medicine, Lund University, Lund, Sweden

41. School of Public Health, St. Mary’s Campus, Imperial College London, London, UK

42. Section for Epidemiology, Department of Public Health, Aarhus University, Aarhus, Denmark

43. Hellenic Health Foundation, Athens, Greece

44. Molecular and Nutritional Epidemiology Unit CSPO (Cancer Research and Prevention Centre), Scientific Institute of Tuscany, Florence, Italy

45. Lunenfeld-Tanenbaum Research Institute of Mount Sinai Hospital, University of Toronto, Toronto, Canada

46. Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Denmark

47. Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark

48. Copenhagen General Population Study, Herlev and Gentofte Hospital, Copenhagen, Denmark

49. Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA

50. Epidemiology Program, University of Hawaii Cancer Center, Honolulu, HI, USA

51. Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA

52. Department of Thoracic Surgery, Division of Epidemiology, Vanderbilt University Medical Center, Nashville, TN, USA

53. Department of Epidemiology and Biostatistics, School of Medicine, Case Western Reserve University, Cleveland, OH, USA

54. IUOPA, University of Oviedo and CIBERESP, Faculty of Medicine, Campus del Cristo s/n, Oviedo, Spain

55. Clalit National Cancer Control Center at Carmel Medical Center and Technion Faculty of Medicine, Haifa, Israel

56. School of Health and Related Research, University of Sheffield, Sheffield, UK

57. Radboud University Medical Center, Nijmegen, The Netherlands

58. Department of Pharmaceutical Sciences, College of Pharmacy, Washington State University, Spokane, WA, USA

59. British Columbia Cancer Agency, Vancouver, Canada

60. Department of Cancer Epidemiology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA

61. Department of Epidemiology, Geisel School of Medicine, Hanover, NH, USA

62. Department of Preventive Medicine, IRCCS Foundation Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy

63. Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

64. Department of Epidemiology, Program in Molecular and Genetic Epidemiology Harvard School of Public Health, Boston, MA, USA

65. Biomedical Data Science Department, Dartmouth College, Hanover, NH, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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