Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations

Author:

Lorenz Susanne12,Barøy Tale13,Sun Jinchang42,Nome Torfinn56,Vodák Daniel1,Bryne Jan-Christian14,Håkelien Anne-Mari1,Fernandez-Cuesta Lynnette78,Möhlendick Birte9,Rieder Harald9,Szuhai Karoly10,Zaikova Olga11,Ahlquist Terje C.56,Thomassen Gard O. S.56,Skotheim Rolf I.56,Lothe Ragnhild A.56,Tarpey Patrick S.12,Campbell Peter12,Flanagan Adrienne1314,Myklebost Ola12,Meza-Zepeda Leonardo A.142

Affiliation:

1. Department of Tumor Biology, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway

2. Norwegian Cancer Genomics Consortium, Norway

3. Institute for Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway

4. Genomics Core Facility, Department of Core Facilities, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway

5. Department of Molecular Oncology, Institute for Cancer research, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway

6. Centre for Cancer Biomedicine, Faculty of Medicine, University of Oslo, Oslo, Norway

7. Department of Translational Genomics, Center of Integrated Oncology Cologne-Bonn, University of Cologne, Cologne, Germany

8. Genetic Cancer Susceptibility Group, International Agency for Research on Cancer (IARC-WHO), Lyon, France

9. Institute for Human Genetics, University Hospital Düsseldorf, Düsseldorf, Germany

10. Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands

11. Clinic for Cancer, Surgery and Transplantation, Oslo University Hospital, Norwegian Radium Hospital, Oslo, Norway

12. Wellcome Trust Sanger Institute, Hinxton, UK

13. Royal National Orthopaedic Hospital, Middlesex, UK

14. UCL Cancer Institute, University College London, London, UK

Publisher

Impact Journals, LLC

Subject

Oncology

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