Phase I/II study of azacitidine and capecitabine/oxaliplatin (CAPOX) in refractory CIMP-high metastatic colorectal cancer: evaluation of circulating methylated vimentin

Author:

Overman Michael J.1,Morris Van1,Moinova Helen2,Manyam Ganiraju3,Ensor Joe4,Lee Michael S.5,Eng Cathy1,Kee Bryan1,Fogelman David1,Shroff Rachna T.1,LaFramboise Thomas6,Mazard Thibault1,Feng Tian1,Hamilton Stanley7,Broom Bradley3,Lutterbaugh James2,Issa Jean-Pierre8,Markowitz Sanford D.2,Kopetz Scott1

Affiliation:

1. Department of Gastrointestinal Medical Oncology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA

2. Department of Medicine and Case Comprehensive Cancer Center, Case Western Reserve University and Case Medical Center, Cleveland, OH, USA

3. Department of Bioinformatics and Computational Biology, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA

4. Houston Methodist Cancer Center, Houston Methodist Research Institute, Houston, TX, USA

5. Division of Hematology/Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA

6. Department of Genetics and Genome Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA

7. Division of Pathology and Laboratory Medicine, The University of Texas M. D. Anderson Cancer Center, Houston, TX, USA

8. Fels Institute for Cancer and Molecular Biology, Temple University, Philadelphia, PA, USA

Publisher

Impact Journals, LLC

Subject

Oncology

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