Liver metastasis of pancreatic cancer: the hepatic microenvironment impacts differentiation and self-renewal capacity of pancreatic ductal epithelial cells

Author:

Knaack Hendrike1,Lenk Lennart2,Philipp Lisa-Marie1,Miarka Lauritz1,Rahn Sascha1,Viol Fabrice3,Hauser Charlotte4,Egberts Jan-Hendrik4,Gundlach Jan-Paul4,Will Olga5,Tiwari Sanjay5,Mikulits Wolfgang6,Schumacher Udo7,Hengstler Jan G.8,Sebens Susanne1

Affiliation:

1. Institute for Experimental Cancer Research, Christian-Albrechts-University Kiel (CAU) and University Medical Center Schleswig-Holstein (UKSH) Campus Kiel, Kiel, Germany

2. Department of Pediatrics, UKSH Campus Kiel, Kiel, Germany

3. Department of Medicine I, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

4. Department of General, Visceral-, Thoracic-, Transplantation- and Pediatric Surgery, UKSH Campus Kiel, Kiel, Germany

5. Molecular Imaging North Competence Center, Clinic of Radiology and Neuroradiology, CAU and UKSH Campus Kiel, Kiel, Germany

6. Department of Medicine I, Division: Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria

7. Centre of Experimental Medicine, Department of Anatomy and Experimental Morphology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany

8. Leibniz Research Centre for Working Environment and Human Factors (IfADo), Technical University Dortmund, Dortmund, Germany

Publisher

Impact Journals, LLC

Subject

Oncology

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