Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR-Reference-Cited by-同舟云学术

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR

Published:2014-01-20 Issue:4 Volume:5 Page:1038-1051
ISSN:1949-2553
Container-title:Oncotarget
language:en
Short-container-title:Oncotarget

Author:

Litzenburger Ulrike M.¹²,Opitz Christiane A.¹²³,Sahm Felix²⁴⁵,Rauschenbach Katharina J.¹²,Trump Saskia⁶,Winter Marcus⁶,Ott Martina¹²,Ochs Katharina¹²,Lutz Christian⁷,Liu Xiangdong⁸,Anastasov Natasa⁹,Lehmann Irina⁶,Höfer Thomas¹⁰,von Deimling Andreas⁴⁵,Wick Wolfgang¹¹¹,Platten Michael¹²

Affiliation:

1. Department of Neurooncology, Neurology Clinic and National Center for Tumor Diseases University Hospital of Heidelberg, Heidelberg, Germany

2. Clinical Cooperation Unit Neuroimmunology and Brain Tumor Immunology, German Cancer Research Center (DKFZ), Heidelberg, Germany

3. Brain Cancer Metabolism Group, German Cancer Research Center (DKFZ), Heidelberg, Germany

4. Department of Neuropathology, Institute of Pathology, University Hospital of Heidelberg, Germany

5. Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany

6. Department for Environmental Immunology, Helmholtz Center for Environmental Research, Leipzig, Germany

7. Heidelberg Pharma GmbH, Ladenburg, Germany

8. Incyte Corporation, Experimental Station, Wilmington, Delaware, USA

9. Institute of Radiation Biology, Helmholtz Center Munich, German Research Center for Environmental Health, Germany

10. Theoretical Systems Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany

11. Clinical Cooperation Unit Neurooncology, German Cancer Research Center (DKFZ), Heidelberg, Germany

Publisher

Impact Journals, LLC

Subject

Oncology

Cited by 250 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The role of nonesterified fatty acids in cancer biology: Focus on tryptophan and related metabolism;Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids;2024-10

2. High Expression of AhR and Environmental Pollution as AhR-Linked Ligands Impact on Oncogenic Signaling Pathways in Western Patients with Gastric Cancer—A Pilot Study;Biomedicines;2024-08-20

3. The Complex World of Kynurenic Acid: Reflections on Biological Issues and Therapeutic Strategy;International Journal of Molecular Sciences;2024-08-20

4. Aryl hydrocarbon receptor: current perspectives on key signaling partners and immunoregulatory role in inflammatory diseases;Frontiers in Immunology;2024-08-15

5. Targeting amino acid-metabolizing enzymes for cancer immunotherapy;Frontiers in Immunology;2024-08-14