Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells' homeostasis

Author:

O’Hagan-Wong Kelsey1,Nadeau Stéphanie2,Carrier-Leclerc Audrey2,Apablaza Felipe1,Hamdy Reggie3,Shum-Tim Dominique4,Rodier Francis25,Colmegna Inés1

Affiliation:

1. Division of Rheumatology, Department of Medicine, McGill University, Montreal, QC, Canada

2. CRCHUM and Institut du Cancer de Montréal, Montreal, QC, Canada

3. Shriners Hospital for Children and Division of Orthopedic Surgery, McGill University, Montreal, QC, Canada

4. Divisions of Cardiac Surgery and Surgical Research, McGill University, Montreal, QC, Canada

5. Department of Radiology, Radio-Oncology and Nuclear Medicine, Université de Montréal, Montreal, QC, Canada

Publisher

Impact Journals, LLC

Subject

Oncology

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