Loss of CtIP disturbs homologous recombination repair and sensitizes breast cancer cells to PARP inhibitors

Author:

Wang Junhui12,Ding Qianshan3,Fujimori Hiroaki14,Motegi Akira5,Miki Yoshio2,Masutani Mitsuko14

Affiliation:

1. Division of Chemotherapy and Clinical Cancer Research, National Cancer Center Research Institute, Tokyo 104-0045, Japan

2. Department of Molecular Genetics, Division of Medical Genomics, Medical Research Institute, Tokyo Medical and Dental University, Tokyo 113-8510, Japan

3. Department of Gastroenterology, Renmin Hospital of Wuhan University, Wuhan 430060, China

4. Department of Frontier Life Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki 852-8588, Japan

5. Department of Radiation Genetics, Kyoto University Graduate School of Medicine, Kyoto 606-8501, Japan

Publisher

Impact Journals, LLC

Subject

Oncology

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