GSTA1 diplotypes affect busulfan clearance and toxicity in children undergoing allogeneic hematopoietic stem cell transplantation: a multicenter study

Author:

Ansari Marc12,Curtis Patricia Huezo-Diaz12,Uppugunduri Chakradhara Rao S.12,Rezgui Mohammed Aziz3,Nava Tiago1345,Mlakar Vid12,Lesne Laurence12,Théoret Yves364,Chalandon Yves7,Dupuis Lee L.8,Schechter Tao8,Bartelink Imke H.910,Boelens Jaap J.9,Bredius Robbert11,Dalle Jean-Hugues12,Azarnoush Saba12,Sedlacek Petr13,Lewis Victor14,Champagne Martin15,Peters Christina16,Bittencourt Henrique36417,Krajinovic Maja3641718

Affiliation:

1. Department of Pediatrics, CANSEARCH Research Laboratory, Faculty of Medicine, Geneva, Switzerland

2. Department of Pediatrics, Onco-Hematology Unit, Geneva University Hospital, Geneva, Switzerland

3. Charles-Bruneau Cancer Center, CHU Sainte-Justine Research Center, Montreal, Quebec, Canada

4. Clinical Pharmacology Unit, CHU Sainte-Justine, Montreal, Quebec, Canada

5. Faculty of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Brazil

6. Department of Pharmacology, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada

7. Department of Medical Specialties, Division of Hematology, Geneva University Hospital, Geneva, Switzerland

8. Department of Haematology/Oncology, Blood and Marrow Transplant Unit, The Hospital for Sick Children, Toronto, Ontario, Canada

9. Pediatric Blood and Marrow Transplantation Program, University Medical Center, Utrecht, The Netherlands

10. Department of Medicine, The University of California San Francisco, San Francisco, CA, USA

11. Department of Pediatrics, Center of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands

12. Pediatric Hematology Department, Robert Debré Hospital, Assistance Publique, Hôpitaux de Paris, Paris, France

13. Department of Pediatric Hematology and Oncology Teaching Hospital, 2nd Medical School, Charles University, Prague, Czech Republic

14. Department of Pediatrics, Alberta Children’s Hospital, Calgary, Alberta, Canada

15. Department of Hematology, Hospital Verdun, Montreal, Quebec, Canada

16. Department of Pediatrics, Stem Cell Transplantation Unit, St Anna Children’s Hospital, Vienna, Austria

17. Department of Pediatrics, Faculty of Medicine, University of Montreal, Montreal, Quebec, Canada

18. On Behalf of the Pediatric Disease Working Party of the European Society for Blood and Marrow Transplantation, Leiden, The Netherlands

Publisher

Impact Journals, LLC

Subject

Oncology

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