CC-115, a dual inhibitor of mTOR kinase and DNA-PK, blocks DNA damage repair pathways and selectively inhibits ATM-deficient cell growth in vitro
Author:
Affiliation:
1. Oncology Research, Celgene Corporation, San Diego, CA 92121, USA
2. Pharmacology, Celgene Corporation, San Diego, CA 92121, USA
3. Medicinal Chemistry, Celgene Corporation, San Diego, CA 92121, USA
Publisher
Impact Journals, LLC
Subject
Oncology
Cited by 54 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Development and therapeutic potential of DNA-dependent protein kinase inhibitors;Bioorganic Chemistry;2024-09
2. Secrets of DNA-PKcs beyond DNA repair;npj Precision Oncology;2024-07-23
3. DNA damage response in brain tumors: A Society for Neuro-Oncology consensus review on mechanisms and translational efforts in neuro-oncology;Neuro-Oncology;2024-03-22
4. Different Impacts of DNA-PK and mTOR Kinase Inhibitors in Combination with Ionizing Radiation on HNSCC and Normal Tissue Cells;Cells;2024-02-06
5. Clinical translation for targeting DNA damage repair in non-small cell lung cancer: a review;Translational Lung Cancer Research;2024-02
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