Inhibition of Miro1 disturbs mitophagy and pancreatic β-cell function interfering insulin release via IRS-Akt-Foxo1 in diabetes

Author:

Chen Lingling12,Liu Chunyan1,Gao Jianfeng1,Xie Zhiwen3,Chan Lawrence W.C.4,Keating Damien J.5,Yang Yibin6,Sun Jiazhong7,Zhou Fuling8,Wei Yongchang9,Men Xiuli10,Yang Sijun1

Affiliation:

1. ABSL-3 Laboratory at the Center for Animal Experiment and Institute of Animal Model for Human Disease, Wuhan University School of Medicine, Wuhan, P. R. China

2. Department of Cell Biology, College of Life Science, Nanjing Normal University, Nanjing, Jiangsu, P.R. China

3. School of Bioscience and Technology , Weifang Medical University, Weifang Shandong, P.R. China

4. Department of Health Technology and Informatics, Hong Kong Polytechnic University, Hong Kong, Hong Kong

5. Department of Human Physiology and Centre for Neuroscience, Flinders University, Adelaide, South Australia, Australia

6. Department of Endocrinology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, P.R. China

7. Department of Respiratory, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, P.R. China

8. Department of Hematology and Radiation, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, P.R. China

9. Department of Medical Oncology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, P.R. China

10. School of Basic Medical Sciences, North China University of Science and Technology, Tangshan, P.R. China

Publisher

Impact Journals, LLC

Subject

Oncology

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