PD-1/PD-L1 interaction up-regulates MDR1/P-gp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways

Author:

Liu Shengwei1,Chen Shuang1,Yuan Weiguang2,Wang Hongyan3,Chen Kewang1,Li Dianjun1,Li Dalin4

Affiliation:

1. Department of Immunology, Harbin Medical University and Heilongjiang Provincial Key Laboratory for Infection and Immunity, Harbin Medical University and Heilongjiang Academy of Medical Science, 150081, Harbin, China

2. Department of Cancer Immunology, Cancer Institute of Harbin Medical University, Department of Cancer Immunology, Heilongjiang Academy of Medical Sciences, 150081, Harbin, China

3. Institute of Harbin Hematology and Oncology, Harbin First Hospital, 150010, Harbin, China

4. Department of Breast Surgery, Harbin Medical University Cancer Hospital, 150081, Harbin, China

Publisher

Impact Journals, LLC

Subject

Oncology

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