Targeting hypoxia-inducible factor-1α (HIF-1α) in combination with antiangiogenic therapy: A phase I trial of bortezomib plus bevacizumab

Author:

Falchook Gerald S1,Wheler Jennifer J2,Naing Aung2,Jackson Edward F3,Janku Filip2,Hong David2,Ng Chaan S4,Tannir Nizar M5,Lawhorn Kristie N6,Huang Mei2,Angelo Laura S7,Vishwamitra Deeksha8,Hess Kenneth9,Howard Adrienne N2,Parkhurst Kristin L2,Amin Hesham M8,Kurzrock Razelle10

Affiliation:

1. Sarah Cannon Research Institute, Denver, CO 80218

2. Department of Investigational Cancer Therapeutics (Phase I Program), The University of Texas MD Anderson Cancer Center, Houston, TX 77030

3. Department of Medical Physics, University of Wisconsin School of Medicine and Public Health, Madison, WI 53705

4. Department of Diagnostic Radiology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030

5. Department of Genitourinary Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030

6. Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX 77030

7. Department of Immunology, Allergy, and Rheumatology, The Center for Human Immunobiology, Texas Children's Hospital/Baylor College of Medicine, Houston, TX 77030

8. Department of Hematopathology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030

9. Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX 77030

10. Center for Personalized Cancer Therapy, Moores Cancer Center, University of California, San Diego, San Diego, CA 92093

Publisher

Impact Journals, LLC

Subject

Oncology

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